Nick Jonas' ex-girlfriend was serving as a co-host for E! News' pre-Emmys red carpet show in downtown Los Angeles, where temperatures reached nearly 100 degrees (37.7 Celsius).
During the live broadcast, the cameras cut to a shot of Culpo and her co-hosts, as the former Miss USA collapsed.
Medics came to the rescue, and Culpo took to Twitter.com to post a photo of herself being taken away in a wheelchair.
She wrote the caption, "When u almost pass out on LIVE TV!", adding, "OMG it is SO HOT out here. Literally just almost passed out."