Actor Donald Faison married his longtime girlfriend Cacee Cobb at the Los Angeles home of his SCRUBS co-star Zach Braff on Saturday (15Dec12).

Jessica Simpson, who is rumoured to be pregnant, walked down the aisle in a black gown as bridesmaid for her best friend Cobb, while Braff and singer Joshua Radin were groomsmen.

The ceremony at Braff's Hollywood Hills home took place under a tent with twinkling white lights and featured a gospel choir.

Braff took to his page to share photos of the special day, including a snap of the groom rehearsing his vows, and later a black-and-white shot of the beaming newlyweds with the caption, "Knots tied."

Radin also posted a picture of himself with Faison and Braff, tweeting, "What a happy day."

Simpson's pop star sister Ashlee and their separated parents, Tina and Joe, were also among the 75 guests who attended the star-studded ceremony.

It is the first marriage for Cobb, Simpson's former personal assistant, while Faison was previously married to Lisa Askey, the mother of his three kids. He also has one son from a previous relationship.

The couple announced its engagement in August 2011.