A city bus slammed into an on-set trailer in the Roxbury section of Boston, United States where 'The Heat' is being made.
The motion picture is about an FBI agent who teams with a local police officer to take down a Russian mobster.
The movie co-stars Melissa McCarthy and is directed by her 'Bridesmaids' director Paul Feig.
At least 11 people were reportedly taken to the hospital after the accident, though none had life-threatening injuries.
A number of people were spotted on stretchers being treated by paramedics.
The accident happened outside the Roxbury Municipal courthouse on Warren Avenue at around 9:30 am, according to website Boston.com.
'Speed' actress Sandra was recently placed third on Forbes magazine's annual highest-paid actresses list.
Her ranking is for the $25 million she earned for forthcoming movie 'Gravity', as well as profits she is still making from 2009 film 'The Blind Side'.
Kristen Stewart was named Hollywood's highest-paid actress.
The 'Twilight Saga' star earned a reported $34.5 million over the last year, narrowly beating Cameron Diaz, who earned $34 million.