Roth owned Greenwich Village club Cafe Wha? which became a haven for 1960s folk stars like Bob Dylan and Mary Travers and comedians Bill Cosby and Richard Pryor.
It was also the place where Animals bass player Chas Chandler first saw Jimi Hendrix and persuaded the unknown guitarist to let him manage his career.
Announcing the sad news on his website, Roth writes, "Uncle Manny has passed away. He was 95 years old. He was happy, laughing and smiling right up ’til the end. His presence already missed. His contributions with us forever."