The designer is to showcase his new collection at 6pm on Sunday, September 18, unlike last season where he opted against a formal catwalk presentation in favour of intimate appointments with key members of the press.
Other designers to show for the first time at the British Fashion Council's event include Teatum Jones - who will present their spring/summer 2012 collection on opening day - and Peter Jensen, who returns from a stint at New York Fashion Week.
As well as showing at London Fashion Week for the first time, Tom is also preparing for the release of his first cosmetics collection.
Tom Ford Beauty's first Cosmetics Collection - a complete range of make-up, skin treatments and luxury brushes - will be on sale in selected stores from September before a widespread launch in October.
Tom Ford Beauty President Caroline Geerlings told The Moodie Report: "The Tom Ford Beauty Collection was designed with the very discerning global luxury consumer in mind, and will only be available in highly-selective points of distribution.
"As this luxury consumer travels the world, the travel retail channel is an ideal way of connecting with her."