The Speed star has been close friends with bachelor Clooney for 20 years but she has confessed she never lusts after the movie hunk because she knows him too well.
She also shockingly declares there are other women who would also turn down the Ocean's Eleven actor despite his dashing looks.
Bullock, who stars with Clooney in new movie Gravity, tells U.K. morning Tv show Daybreak, "We've known each other for so long, sexy is gone. Not that he's not sexy because he is very, very handsome. If you like that kind of dashing, charming, smart, talented, successful kind of thing. It's not everyone's cup of tea."
The actress will be pleased to know the feeling is mutual - last month (Oct13) Clooney revealed he has ruled out ever dating his close pal because she once went out with one of his friends.