The boyband stars, who also led the charge at last year's (13) prizegiving, were named winners of two top awards - Favorite Music Group and Favorite Song for Story Of My Life.
Meanwhile, in the movie categories, Lawrence picked up Favorite Movie Actress and Favorite Female Buttkicker for her turn as Katniss Everdeen in The Hunger Games: Catching Fire. The film was also named Favorite Movie.
Selena Gomez was on hand to claim her prize for Favorite Female Singer, and grew emotional as she collected the ceremony's blimp-themed trophy.
She said, "Thank you so much. This has been such an amazing year already for me and I just have to say that you guys have been the most loyal, dedicated people in my life, because you continuously, every year, bless me with the opportunity to do what I love, so thank you so much. You guys are awesome, and this is for you. So, thank you."
Justin Timberlake, another no-show, was named Favorite Male Singer, while Adam Sandler collected his prize for Favorite Movie Actor.
As usual, some celebrities weren't so lucky, and instead of walking away with awards, sloped off the stage covered in the event's famous green gunge. Host Mark Wahlberg, Kaley Cuoco and Cody Simpson were among the slimed stars.
The full list of winners at the Nickelodeon Kids' Choice Awards is:
Favorite Movie - The Hunger Games: Catching Fire
Favorite Movie Actor - Adam Sandler (Grown-Ups 2)
Favorite Movie Actress - Jennifer Lawrence (The Hunger Games: Catching Fire)
Favorite Animated Movie - Frozen
Favorite Voice From An Animated Animated Movie - Miranda Cosgrove (Despicable Me 2)
Favorite Male Buttkicker - Robert Downey Jr. (Iron Man 3)
Favorite Female Buttkicker - Jennifer Lawrence (The Hunger Games: Catching Fire)
Favorite TV Show - Austin & Ally
Favorite TV Actress - Ariana Grande (Sam & Kat)
Favorite Reality Show - Wipeout
Favorite Cartoon - Spongebob Squarepants
Favorite Animated Animal Sidekick - Patrick Star (Spongebob Squarepants)
Favorite Music Group - One Direction
Favorite Male Singer - Justin Timberlake
Favorite Female Singer - Selena Gomez
Favorite Song - Story Of My Life (One Direction)
Favorite Book - Diary Of A Wimpy Kid
Favorite Funny Star - Kevin Hart
Favorite Video Game - Just Dance 2014
Lifetime Achievement Award - Dan Schneider.