Ex-cop Luke (Statham) is working as a cage fighter when he runs afoul of the Russian mafia, because they lose millions stupidly betting against him.
Brutally hunted by the boss' son (Sikora), Luke is contemplating suicide when he spots little Mei (Chan) being chased by the Chinese mob. Suddenly kicking into gear, he rescues her and discovers that she's a numerical prodigy who has memorised an important sequence of numbers. But now the Russians, Chinese and a gang of rogue cops led by a New York police captain (Burke) are all after them.
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Former elite agent Luke White lives in New York and is all too familiar with the city's seedy underbelly, which crawls with corrupt policemen, killers and gangsters. The policemen, along with the Russian mafia and the Triads, are all looking for New York's Most Wanted, who has memorised a very long safe combination that is of the utmost importance.
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