It's hard to think about the world of comic book movies without 'Deadpool' immediately springing to mind. The film was one of 2016's biggest successes, despite being slapped with an R-rating in the US, and went on to break all sorts of records while catapulting Ryan Reynolds into the world of much-adored superheroes.

Ryan Reynolds as Marvel Comics character DeadpoolRyan Reynolds as Marvel Comics character Deadpool

Earlier this year, Reynolds announced the news that Zazie Beetz had joined the cast of 'Deadpool 2' in a now-deleted tweet, using dominoes to reveal that she'd be taking on the character Domino.

'Deadpool' creator Rob Liefeld spoke about the chemistry that will have to be shared between Beetz and Reynolds in the upcoming film release - something he's confident will be there.

Speaking to "Domino is all about, as an actress and as the character that is going to be on the screen you already allude to it, it's all about the sass. You gotta understand, you're gonna go up against Wade Wilson, who is, in this movie is Ryan Reynolds and trust... I'm telling you, having been around Ryan multiple times that mouth cannot be stopped. He... It's point... I don't think he can say the jokes as fast as they are backed up in his head. So, you need... Some of these people be like 'Oh hey, this girl should have been Domino', and pick out actress a through z and I'd be like 'I'm not sure they can keep up with him', and 'oh my gosh, I'm not sure that Ryan's gonna keep up with her.'

"I think Ryan Reynolds is gonna have to work hard to keep up with Zazie. I mean, wow. You just go 'That chemistry is going to be spectacular'. And that's what it comes down to is the chemistry with these characters."

He added: "I mean, Ryan's gotta have a strong lead opposite him so Zazie is going to be great."

Check out this new footage of 'Deadpool' released by Ryan Reynolds below:

It's fantastic to hear that the man who created Deadpool is excited about the casting for the second movie in the series, but now a lot of talk has returned to who exactly will be playing the film's expected third lead, Cable. Michael Shannon - who played General Zod in the 'Man Of Steel' movie - is the current frontrunner, but names such as Brad Pitt, David Harbour and Russell Crowe are all also being thrown around.

More: Ryan Reynolds honoured with a star on the Hollywood Walk of Fame

'Deadpool 2' comes to movie theatres on March 2, 2018, following the release of Rob Liefeld's new graphic novel 'Deadpool: Bad Blood' on May 17, 2017.