Believe it or not, the internalized bioterror story has been made before, and like Oktober it didn't make much of an impact (it was called Contaminated Man and went straight to cable as far as I remember). Why doesn't this story work? Because in a movie, when you can't see the danger, it doesn't exist. The deadliness of the killer enzyme just isn't that credible as a threat. (Contrast with Outbreak, which at least had wheezing, sore-covered cadavers popping up all over the place. Enzyme boy doesn't even know he's the carrier monkey.)
Continue reading: Oktober Review
There's already an Oscars buzz surrounding this movie.