The singer - who turned 41 on Wednesday (16.09.09) - and his wife Jennifer Lopez were in Washington D.C. for the Congressional Hispanic Caucus Institute's Awards Gala, which the US leader also attended.
Obama reportedly convinced a group of politicians to sing to Marc backstage at the event.
A jovial Obama also teased Marc about his sex-symbol status, claiming at the Hispanic Caucus dinner that chairwoman Nydia Velazquez thought he was good looking.
President Obama is quoted as saying: "I'm telling you J.Lo, watch out!"
Marc and Jennifer then celebrated his big day at the W hotel's P.O.V. Lounge.
The bash started at 10.30pm, and guests including Marc's family, agent Benny Medina and Miami Dolphins coach Wayne Huizenga - who Marc has grown close to after buying a stake in the American football team - partied until 2am.
Marc was given a five-tier 'Congratulations and Happy Birthday!' chocolate cake with fondant icing to mark his big day, although further details of the party are as yet unknown.
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