Madonna's adopted home city of London will be dancing to the beat of the MATERIAL GIRL this weekend - with a series of club nights to mark her birthday.
Salvador + Amanda, near Leicester Square, will be pumping out retrobeat tunes and staging performances from Tranni Danni and Heidi Liscious in honour of the Queen of Pop's 50th.
The G-A-Y Late Bar, off Charing Cross Road, is hosting the Sticky + Sweet Birthday Party - featuring eight hours of Madonna songs and videos, and the chance to win Madonna-related prizes.
In Scotland, the Dumfries Pride rally coincides with the singer's birthday - and organisers are celebrating by installing a Madonna Area, featuring non-stop music, a Vogue dancing competition, and a prize for the best Madonna lookalike.
Meanwhile, a Madonna Party will be held at the Globe Theatre in Brisbane, Australia, with entertainment including a screening of Desperately Seeking Susan and non-stop Madonna tunes all night.