The pop superstar - who is a proud New Yorker - has been personally chosen by Major Michael Bloomberg to push a Waterford Crystal button and drop the ball into the crowd at 11.59pm on Saturday night (31.12.11).
Every year the major picks a special guest to lead the countdown and previous choices have included former US President Bill Clinton and his wife Hilary Clinton, boxing legend Muhammad Ali and Rudy Giuliani.
Over one million people are expected to join the celebrations in the 'Big Apple'.
The 'Marry the Night' singer will also appear on Japanese broadcaster Nhk's New Year's Eve TV spectacular 'Kohaku Uta Gassen' as part of a live satellite link-up from New York.
Because of the time difference Gaga will 'celebrate' New Year's twice as she will appear on the Japanese TV show before the big countdown happens in the US.