The 'Fashion Police' host doesn't think readers have the right to criticise the 'Keeping Up With The Kardashians' star and her rapper fiance, Kanye West, who front the latest edition of the magazine, after stars like Sarah Michelle Gellar have threatened to cancel their subscription to the prestigious publication.
In a blog post titled 'MY THOUGHTS ON KIM AND KANYE ON VOGUE', she wrote: ''People are even going so far as to cancel their subscriptions or bloggers [are] taking down the link to Vogue magazine. I don't want to even go into the awful things people have said about them.
''I find this disgusting. Regardless of whether or not you think Kim and Kanye are worthy enough [to] be on the cover ... it's not your decision to make. I do believe that would be up to [Editor] Anna Wintour.''
Kelly urges fans to ''be happy'' for Kim and Kanye, who have nine-month-old daughter North together and are expected to wed this May.
She explained: ''So back off, stop s**ting on people's dreams that have come true and try for once to be happy for others' success. Stop raining on their parade!''
However, Kelly admits it looks like the cover of US Prom magazine, a publication which covers teen stars.
She added: ''There is no denying that it looks like a really beautiful picture for the cover of Prom magazine so I understand why the fashionistas of the world would not like it.''
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The show will be seen by everybody at the same time.
The Scottish comedian has been speaking about gaining a knighthood in the Queen's Birthday Honours List.