The British band - who were named Best Act In The World Today at the recent Q Awards - have joined the festival's current line-up, which already includes Foo Fighters, Kings Of Leon and reformed Britpop band Pulp.
John Giddings, promoter for the event, explained: "We wanted the kings of rock 'n' roll every night for our tenth birthday and the choices were obvious.
"Kasabian have reignited UK rock music and taken the mantle, long may they reign. It will be a riotous crowd-pleasing end to the weekend and I think that Jimi Hendrix would approve of our choices!"
The 2011 event is to take place from June 10 to 12 at the Seaclose Park venue on the British island.