Justin Timberlake and Macklemore & Ryan Lewis will go head-to-head for the honour of Best U.S. Act as they lead the MTV 2013 Europe Music Awards with five nominations each.

SexyBack hitmaker Timberlake has been shortlisted for Best Male, Best Live, Best Video for Mirrors, and Best Look, and MACklemore & Ryan Lewis are up for Best New, Best Song for Thrift Shop, Best World Stage, and Best Hip Hop.

The musicians will face off against each other and stars including Miley Cyrus and Robin Thicke for the Best U.S. Act title.

Cyrus and Thicke are each up for four awards, as are Justin Bieber - including Best Male and Best Pop - and Lady Gaga, whose nominations include Best Female and Best Video for Applause.

Boyband One Direction are up for Best Pop and Best U.K. and Ireland Act, Katy Perry has scored nominations in the Best Pop and Best Female categories, and Rihanna is also in the running for two awards including Best Look and Best Song for Diamonds.

The awards ceremony will take place in Amsterdam, Netherlands in November (13).

The full list of main nominations is as follows:

Best Song:

Bruno Mars - Locked Out Of Heaven

Daft Punk - Get Lucky (ft. Pharrell Williams)

MACklemore & Ryan Lewis - Thrift Shop (ft. Wanz)

Rihanna - Diamonds

Robin Thicke - Blurred Lines (ft. T.I. & Pharrell)

Best Pop:

Justin Bieber

Katy Perry

Miley Cyrus

One Direction

Taylor Swift

Best Female:

Katy Perry

Lady Gaga

Miley Cyrus

Selena Gomez

Taylor Swift

Best Male:

Bruno Mars

Eminem

Jay Z

Justin Bieber

Justin Timberlake

Best Live:

Beyonce

Green Day

Justin Timberlake

Pink

Taylor Swift

Best New:

Bastille

Icona Pop

Imagine Dragons

MACklemore & Ryan Lewis

Rudimental

Best Video:

Justin Timberlake - Mirrors

Lady Gaga - Applause

Miley Cyrus - Wrecking Ball

Robin Thicke - Blurred Lines (ft. T.I. & Pharrell)

Thirty Seconds To Mars - Up In The Air

Best Rock:

Black Sabbath

Green Day

Kings Of Leon

Queens Of The Stone Age

The Killers

Best Alternative:

Arctic Monkeys

Fall Out Boy

Franz Ferdinand

Paramore

Thirty Seconds To Mars

Best Hip Hop:

Drake

Eminem

Jay Z

Kanye West

MACklemore & Ryan Lewis

Best Electronic:

Afrojack

Avicii

Calvin Harris

Daft Punk

Skrillex

Best U.K. & Ireland Act:

Calvin Harris

Ellie Goulding

Olly Murs

One Direction

Rudimental.