The 'Dark Shadows' actor was introduced by Aerosmith front man Steven Tyler and guitarist Joe Perry to received the award for his contributions to the film industry and for entertaining generations throughout his career.
After watching a montage of his films at the ceremony hosted by Russell Brand, Johnny joked: ''This is the get of the business award. Based on watching all of those clips there is clearly something wrong with me.''
'The Hunger Games' was the big winner of the night, picking up gongs in four categories, Best Female and Best Male for Jennifer Lawrence and Joshua Hutcherson along with Best Fight and Best On-Screen Transformation.
'Bridesmaids' took home two awards, with Melissa McCarthy winning for Best Comedia Performance while the entire cast shared the Gut Wrenching Performance award for the scenes where food poisoning turned a wedding dress fitting in to a disaster.
Kristen Stewart and Robert Pattinson took home her fourth-straight win in the Best Kiss category for 'The Twilight Saga: Breaking Dawn - Part 1' while Jennifer Aniston was a surprise winner for Dirtbag of the Year for her role in 'Horrible Bosses'.
The audience was also treated to a sneak peak of 'The Dark Knight Rises,' introduced by director, writer and producer Christopher Nolan, along with cast members Christian Bale, Joseph Gordon-Levitt and Gary Oldman.
The 2012 MTV Movie Awards will be screened on MTV tonight (04.06.12) at 9pm and tomorrow (05.06.12) at 10.30pm.
Winners of the 2012 MTV Movie Awards
MOVIE OF THE YEAR
'The Twilight Saga: Breaking Dawn - Part 1'
BEST FEMALE PERFORMANCE
Jennifer Lawrence - 'The Hunger Games'
BEST MALE PERFORMANCE
Josh Hutcherson - The Hunger Games'
Shailene Woodley -'The Descendant'
BEST COMEDIC PERFORMANCE
Melissa McCarthy - 'Bridesmaids'
'Harry Potter and the Deathly Hallows: Part 2'
BEST ON-SCREEN TRANSFORMATION*
Elizabeth Banks - 'The Hunger Games'
Jennifer Lawrence and Josh Hutcherson vs. Alexander Ludwig - 'The Hunger Games'
Robert Pattinson and Kristen Stewart - 'The Twilight Saga: Breaking Dawn - Part 1'
BEST GUT-WRENCHING PERFORMANCE
BEST ON-SCREEN DIRTBAG
Jennifer Aniston - 'Horrible Bosses'
'Party Rock Anthem' LMFAO - '21 Jump Street'
It's been five years since the last Harry Potter movie, and J.K. Rowling has been...
Jack Sparrow finds himself in constant trouble with the law; not only is his name...
This much more light-hearted sequel reinvigorates the franchise after Disney's quirky but murky 2010 reboot...
As Alice is once again taken into the magical and mysterious world that she's somehow...
For a biopic of a real-life person, this feels like an oddly standard mob thriller....
Alice once again returns to Wonderland and meets a lot of familiar faces. This time...
Edward Scissorhands is no ordinary boy, as his name may tell. Created by a genius...
Irish-American criminal mastermind Whitey Bulger was arguably one of the most dangerous men in America...
Sometimes, the greatest hiding place is in plain sight. For twelve years from the mid-1990s,...
Despite a superior cast and terrific-looking production values, this mystery romp is a misfire on...