The rapper-turned-actress will also welcome Jamie Foxx, Sharon Stone and Jake Gyllenhaal onto the set during her first week as a Tv personality.
Announcing her impressive guest list, Queen Latifah says, "I cannot think of a more talented and fun group of people to share the stage with in celebration of the launch of my new show.
"I am honoured to have the support of so many long-time friends and colleagues as I begin this journey, and I look forward to sharing this experience with all of them and with the many new friends I will make along the way."
The Chicago star reveals she'll also be chatting to rapper Jay Z on an upcoming show, while President Barack Obama and his wife Michelle have an open invitation to appear.
According to The Hollywood Reporter, the show will also chronicle rap star Pitbull's attempts to open of a charter school in his hometown of Miami.