The actor, who has just been voted People magazine's Hottest Bachelor, has been single since splitting from fiancee Audra Marie in 2011, and although he has since been linked to French cabaret dancer Veronique Lazoore and model Bridget Peters, he admits he is still looking for 'The One'.
He tells the publication, "I'm at my best when I have someone to wake up next to and come home to. I know she's out there."
Manganiello, who is part Sicilian, reveals he is looking for a woman who can handle his "hot-blooded" and "passionate" personality, stating, "If you don't like spicy, then maybe I'm not for you. I like hugs and kisses and snuggling. I'm a physical person. If you're not, then it ain't gonna (sic) work. Also, passive-aggressive and sarcastic does not work for me. It's such a turn-off."
Discussing his ideal woman, he says, "Girls that do squats. I love a butt. Sofia Vergara, that's it. She's got that Latin thing going. She's got the butt, she's got curves, she's got a beautiful face, beautiful hair, just gorgeous. And she's feisty!"
And Manganiello insists any potential partner will have to be able to "keep up" with his crazy lifestyle.
He explains, "I haven't met someone who can keep up. For somebody to have her own identity and maturity, and then to be available enough or adventurous enough to pack a suitcase, grab a passport and take off with me for a year or two, takes a very special person. You wonder, 'Is this person going to be able to handle this big life...?'
"Sometimes I sit in my house and I look at how far I've come in life, and it's always so much better when you have somebody to share that with."
Manganiello has a shot at dating Vergara - she split from her fiance Nick Loeb in May (14).