The outspoken comedienne even stunned her daughter Melissa with her remarks, which followed the troubled actress' revelation on her 'Lindsay' reality show at the weekend that she had recently lost a baby.
Asked what she thought about the news, Joan, 80, told TMZ: ''I hope she kept it.''
As Melissa recoiled in horror, she added: ''Excuse me, what do you think I am? I was born with a coat hanger in my ear.''
The 'Fashion Police' host then laughed when she was asked if she thought the 'Mean Girls' star would have made a good mother.
She replied: ''She would have been diapering the wrong end.''
Lindsay, 27, made the revelation on camera when explaining why she had taken a break from filming the OWN show, which chronicled her attempts to relaunch her career following her sixth stint in rehab.
She said: ''No one knows this, and we can finish after this, I had a miscarriage for the two weeks that I took off.''
After a long pause, the flame-haired beauty added: ''It's a very long story,'' and failed to offer any other details, including who the father of her unborn child was.
He also slapped a jet-lagged Taylor Hawkins.
The acclaimed performer had just cancelled touring due to a battle with cancer.
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