The outspoken comedienne even stunned her daughter Melissa with her remarks, which followed the troubled actress' revelation on her 'Lindsay' reality show at the weekend that she had recently lost a baby.
Asked what she thought about the news, Joan, 80, told TMZ: ''I hope she kept it.''
As Melissa recoiled in horror, she added: ''Excuse me, what do you think I am? I was born with a coat hanger in my ear.''
The 'Fashion Police' host then laughed when she was asked if she thought the 'Mean Girls' star would have made a good mother.
She replied: ''She would have been diapering the wrong end.''
Lindsay, 27, made the revelation on camera when explaining why she had taken a break from filming the OWN show, which chronicled her attempts to relaunch her career following her sixth stint in rehab.
She said: ''No one knows this, and we can finish after this, I had a miscarriage for the two weeks that I took off.''
After a long pause, the flame-haired beauty added: ''It's a very long story,'' and failed to offer any other details, including who the father of her unborn child was.
All I Want For Christmas is widely regarded as one of the best festive tunes every year
Pearl Jam announced 14 dates in the UK and Europe in June and July 2018.
Standing three apples high, the tiny Smurfs live happily and peacefully in their medieval Smurfs...
Filmmakers Stern and Sundberg, better known for punchy political films like The Devil Came on...