HOUSE heart-throb Jesse Spencer is desperate to return to his soap opera roots with a cameo appearance in hit Australian drama Neighbours.

The actor shot to TV fame as aspiring carpenter BILLY KENNEDY in the show before leaving in 2000.

Despite his success since, alongside Hugh Laurie in medical drama House, the 27-year-old misses the fictional Ramsay Street.

He is reportedly bidding to stage a second cameo comeback, after briefly reuniting with the cast on a special 20th anniversary episode last year (05).