The producer's most famous collaborators and label artists performed at the Fox Theater in Atlanta, Georgia, with Jay Z giving a rendition of Money Ain't a Thang with man of the hour Dupri.
Usher and Ludacris performed their huge hit Yeah! with Lil Jon, and the R&B singer praised Dupri for all his help throughout his chart career, telling the crowd, "I've made more hits with this man than anyone else."
Nineties hip-hop duo Kris Kross reunited for the tribute show to rap their iconic single Jump, while Monica, Nelly and Bow Wow also performed.
Carey then made an appearance, wheeling out a huge cake to mark the special occasion and announcing, "Congratulations to my friend, Jd!"
Dupri told the audience, "Wow... this is crazy. We did it! Thank you everyone - the fans, the artists... ain't nobody f**king with my clique!"