Curtis was only 19 years old when she played Laurie Strode in John Carpenter's classic film and she still has a lot of keepsakes from the set, including four masks worn by killer Michael Myers.
Now one of them is going under the hammer to help the actress raise money for the Children's Hospital Los Angeles.
The sale began on Charitybuzz.com on Tuesday (15Oct13) and will run until Halloween (31Oct13).
Curtis tells Ew.com, "I had this epiphany about a year ago after I realised that the people that love horror films love them with a fervour that I maybe don't even understand. I realised that there's a way to monetise my fame and to try to connect it to something that can raise money for charity.
"I'm not someone who hoards things, but I realised that I have a few things that are potentially very valuable. And the first thing I have are these masks. The second thing I have are the actual clapboards for syncing the film that are at the beginning of every shot in a movie. And I have every one of them from every movie, including the original Halloween clapboard.
"This mask is actually signed by as many people as I could get to, so I would be hard-pressed to imagine anyone has anything with those signatures on it... This mask has a group of signatures that would be very hard to replicate, and I've numbered them. There are five masks, and this is number one of five that is going up for auction."