The 28-year-old model - who recently starred in Spanish Vogue - admitted she had a lot of fun on the shoot, which was captured by famed photographer Mario Testino and saw her soccer star beau pose naked.
She told Vogue.co.uk: ''You know, the Vogue cover was so much fun, it was a great team.''
''You can never go wrong with Mario Testino.''
Irina is also set to make her acting debut later this month opposite Dwayne 'The Rock' Johnson in the mythical epic 'Hercules'.
The stunning brunette enjoyed the transition from model to actress and is keen to take-on some more big-screen roles in the future.
She explained: ''When you're on set for modelling, even for a lingerie shoot, you have maybe 10 people behind the camera, but on a film you have 200 people!
''You have to perform and you have to forget that you're a model; you have to be real. It's very different. You have to really believe in your character.
''I love fashion, and I love to be a model, but definitely I enjoyed making this movie and I would like to act again.''
'Wilson', starring both Dern and Harrelson, is released in U.S. cinemas on March 24th.
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