Kerry Ellis, who first took on the role in 2006 when she became the first British Elphaba, will replace Willemijn Verkaik in London from 4 August to 25 October (14).
Verkaik, who will play her final performance as Elphaba on Saturday (19Jul14), has been forced to step out of the spotlight after a seven-year international run to have surgery on her back.
Ellis says, "It is an absolute thrill for me to be returning to this amazing show and the incredible role of Elphaba that is so very special to me. I can't wait to be green again and join this fantastic cast."
The London production of Wicked is the 10th longest running show in the West End.