The actress has won rave reviews for her role as the monarch in Stephen Daldry's West End production, which dramatises pivotal meetings between the Queen and 12 British prime ministers over 60 years - and now U.S. theatre fans will have the chance to see it.
Britain's Daily Mail reports the show is set to open in New York in 2014, and Mirren will resume her role in the play, which is due to finish its London run in June (13).
The actress says, "There are talks and negotiations going on now, and I will be going to do the play over there around this time next year."
Mirren reveals she has told producers to carry on the show with another star playing the monarch, adding, "I have other commitments now, but I have urged the producers to continue with another actress, at another theatre. It's such a good piece, and there are so many people unable to get tickets, that they should re-mount it."