Holy crap, William Hurt and Jennifer Tilly are married. After arriving in Amsterdam on an animated plane, the couple checks into a fancy hotel and promptly loses their mute daughter, who promptly witnesses a murder and ends up on the run from the killers (including Michael Chiklis, TV's The Commish!).
Between the wholly unbelievable and shoddy police work (there's no sign of a struggle... never mind all the bullet holes!) and Hurt's awful "southern" accent, Do Not Disturb makes it awfully difficult to suspend disbelief. But Do Not Disturb is suspenseful enough to hold your interest, more or less.
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