Annie Lennox and Dave Stewart will take part in The Night That Changed America: A Grammy Salute To The Beatles, marking their first appearance onstage together since 2003.
John Mayer and Keith Urban will team up to perform Don't Let Me Down at the gig, while Alicia Keys and John Legend will tackle Let It Be. Maroon 5 also will hit the stage.
Grammy Awards producer Ken Ehrlich says, "When it came around to booking this show, what I felt was important was to try and find those artists who not only would be able to interpret Beatles songs, but would also have an... understanding of what they meant."
The show will be taped at the Los Angeles Convention Center on 27 January (14), a day after the Grammy Awards.
The Fab Four have been announced as the recipients of an honorary lifetime achievement Grammy this year (14) and they will be feted at a special ceremony before the main awards show.
The special concert will air on America's CBS network on 9 February (14), exactly 50 years after the Beatles made their U.S. debut on The Ed Sullivan Show.