The singers will co-headline a world tour - expected to include more than 60 dates - set to kick off in Venezuela, South America, this June.
Dates are also being lined up in the United States, Europe and Asia, although these have yet to be confirmed.
The tour will be Jennifer's first full world tour, and she is gearing up for a spectacular stage show.
A source told Celebuzz.com: ''Jennifer and her team have blocked out more than a month of their schedules, beginning May 4, to start intense rehearsals, each day, at a sound stage in the Los Angeles area.
''This will be a huge tour, complete with a lavish set, full band and team of dancers.''
'Hero' singer Enrique was announced as the support act for Britney Spears' world tour last year, but withdrew just hours after the announcement was made. At the time he apologised for the ''confusion,'' but it was rumoured he was not happy that he would be the support act, rather than having equal billing.
The source said Jennifer ''is very excited about Enrique joining the tour.''
It is expected the pair will duet on their recent track 'Mouth 2 Mouth' from Enrique's 'Euphoria' album during the tour.