The rapper announced the news by posting a 15-second video online on Friday (08Nov13). In the cryptic footage, a mystery man places a mixtape in a boombox placed on a European street and presses play.
As he walks off, the music to Eminem's hit single Berzerk plays - and the screen cuts to an ad for the latest Mtv awards show.
The rap star will join Miley Cyrus, The Killers, Robin Thicke and Katy Perry on the bill.
Eminem has 13 EMA wins - more than any other artist. Justin Timberlake and MACklemore & Ryan Lewis lead this year's nominations with five apiece.