Chelsea Handler claims she has been mocking Angelina Jolie for years.
The outspoken comic launched a foul-mouthed tirade against the actress - who infamously locked lips with her brother James Haven at the 2000 Academy Awards - during a stand-up show on Friday (03.12.10) but insists the attack was nothing to do with her Friendship with Jennifer Aniston who used to be married to Angelina's current partner Brad Pitt.
Chelsea said: "I've been making fun of Angelina Jolie since she made out with her brother.
"If I've learned nothing from this, it's to write some new jokes."
It had previously been suggested that Chelsea branded Angelina a "homewrecker" and a "f***ing ****" in support of Jennifer.
One source said: "Chelsea hates Angelina and doesn't for one second buy that she is this good person rescuing children in need around the world. Everyone in Hollywood is scared to say what they really think about Angelina except Chelsea.
"She thinks Angie stole another woman's husband and should be called out on it."
Chelsea spent the recent Thanksgiving holiday in Mexico with Jennifer, and pals believe the outspoken presenter is a good influence on the former 'Friends' star.
The source added to gossip website PopEater: "Chelsea is the best thing to happen to Jen. Chelsea isn't afraid to tell Jen the truth even if it is painful. In the past Jen has made it clear that she doesn't want her friends talking about what went down between her, Brad and Angie.
"But Chelsea doesn't care. She thinks Angelina has used her kids to manipulate her image and gotten away with destroying a beautiful marriage. She's going to shout it from the roof tops whether Jen likes it or not."