The actress made her first high-profile public appearance since undergoing treatment for Bipolar II disorder - which is known as manic depression - as she presented two prizes at the ceremony, which recognises the achievements of actors in live Broadway theatre.
Catherine wore a radiant red gown as she handed out the gongs for Best Performance by an Actor in a Leading Role in a Play and Best Performance by an Actor in a Leading Role in a Musical, which were won by Mark Rylance for 'Jerusalem' and Norbert Leo Butz for 'Catch Me If You Can' respectively.
And the 41-year-old 'Chicago' star - who picked up a Tony last year for her performance in the Broadway revival of 'A Little Night Music' - admitted she would consider doing a show in London, but is yet to receive any offers.
She said: "I got my big break tap dancing in '42nd Street' in London. That's where it all started and I would love to do a show in London again but no one has asked me."
'South Park' creators Trey Parker and Matt Stone's 'The Book of Mormon' dominated the awards, winning nine accolades including Best Musical, Best Book of a Musical and Best Original Score (Music and/or Lyrics) Written for the Theatre.
The 'Normal Heart' won three gongs including Best Revival of a Musical at the event which was held at the Beacon Theatre in New York City.
American Theatre Wing's 65th annual Tony Awards full list of winners:
Best Play - 'War Horse'
Best Musical - 'The Book of Mormon'
Best Book of a Musical - 'The Book of Mormon'
Best Original Score (Music and/or Lyrics) Written for the Theatre - 'The Book of Mormon'
Best Revival of a Play - 'The Normal Heart'
Best Revival of a Musical - 'Anything Goes'
Best Performance by an Actor in a Leading Role in a Play - Mark Rylance, 'Jerusalem'
Best Performance by an Actress in a Leading Role in a Play - Frances McDormand, 'Good People'
Best Performance by an Actor in a Leading Role in a Musical - Norbert Leo Butz, 'Catch Me If You Can'
Best Performance by an Actress in a Leading Role in a Musical - Sutton Foster, 'Anything Goes'
Best Performance by an Actor in a Featured Role in a Play - John Benjamin Hickey, 'The Normal Heart
Best Performance by an Actress in a Featured Role in a Play - Ellen Barkin, 'The Normal Heart'
Best Performance by an Actor in a Featured Role in a Musical - John Larroquette, 'How to Succeed in Business Without Really Trying'
Best Performance by an Actress in a Featured Role in a Musical - Nikki M. James, 'The Book of Mormon'
Best Scenic Design of a Play - Rae Smith, 'War Horse'
Best Scenic Design of a Musical - Scott Pask, 'The Book of Mormon'
Best Costume Design of a Play - Desmond Heeley, 'The Importance of Being Earnest'
Best Costume Design of a Musical - Tim Chappel and Lizzy Gardiner, 'Priscilla Queen of the Desert'
Best Lighting Design of a Play - Paule Constable, 'War Horse'
Best Lighting Design of a Musical - Brian MacDevitt, 'The Book of Mormon'
Best Sound Design of a Play - Christopher Shutt, 'War Horse'
Best Sound Design of a Musical - Brian Ronan, 'The Book of Mormon'
Best Direction of a Play - Marianne Elliott and Tom Morris, 'War Horse'
Best Direction of a Musical - Casey Nicholaw and Trey Parker, 'The Book of Mormon'
Best Choreography - Kathleen Marshall, 'Anything Goes'
Best Orchestrations - Larry Hochman and Stephen Oremus, 'The Book of Mormon'
Special Tony Award for Lifetime Achievement in the Theatre - Athol Fugard and Philip J. Smith
Regional Theatre Tony Award - Lookingglass Theatre Company 'Chicago, Ill'
Isabelle Stevenson Award - Eve Ensler
Special Tony Award - Handspring Puppet Company
Tony Honor for Excellence in the Theatre - William Berloni, The Drama Book Shop and Sharon Jensen and Alliance for Inclusion in the Arts
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