The Venezuelan designer - who counts Renee Zellweger, Cate Blanchett and Kristen Scott-Thomas among her celebrity clients - believes the late former US First Lady has a huge influence on what women wear, almost 16 years after her death.
She revealed: "The influence of Jackie's style can still be seen now on the catwalks, every designer shows a look inspired by her. She was very classic, but with a modern twist.
"I've worked with so many amazing women. What these stylish women all have in common is the knowledge of what looks well on them - the knowledge of herself."
Carolina, 71, was recently in London for the opening of her first ever UK store - CH by Carolina Herrera on Mount Street in London.
Talking about the launch, she told vogue.com: "We waited a long time to find just the right spot. I like that it's a new place - Mount Street has become a destination in the same way that South Molton Street did."