Sean (Kerr Smith), a struggling film editor for a B-movie studio, heads out onto the road from LA to deliver a vintage Mercedes and attend his sister's wedding in Florida. Along the way, he picks up Nick (Brendan Fehr), a hitchhiker with a lame beard who sweats profusely and holds a hidden agenda. During a rest stop, Sean and Nick pick up a dazed girl named Megan (Izabella Miko), an apparent vampire victim who was left for dead by a nightcrawler gang roaming the countryside.
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The former President quoted Nelson Mandela in the wake of the violence.